People want to find ways to stay healthy and active as they age. Scientific research has discovered NMN, a new compound that helps fight aging in our cells.
As science advances, more and more people are taking NMN supplements. It can support youthful vitality and slow the aging process. NMN supplements do this by boosting NAD+ levels. NAD+ is an essential molecule for energy production, DNA repair, and overall health.
However, manufacturers create NMN supplements with varying quality. As more and more brands flood the market, many companies market low-quality products that do more harm than good. Knowing how to tell good products from those that might not meet your expectations is important. From purity and bioavail ability to complementary ingredients and brand reputation, choosing the best NMN supplement requires careful consideration.
This article will guide you through the information you need to choose the right NMN supplement for your needs. To boost energy, improve meta bolism, or fight aging, you will find helpful insights here. These suggestions will assist you in making an intelligent decision.
Key Takeaways:
- Researchers have clinically proven that only oral supplements of NMN are effective, despite its different delivery methods.
- Dosages of NMN supplements can vary. Knowing what is safe and effective based on clinical trials is important.
- The quality of supplements varies widely. Look for third-party certification to ensure quality and purity.
- Search for ingredients that you can combine with NMN to produce better results.
NAD and Cellular Health
As mentioned before, NAD+ is a coenzyme found in every cell of the human body. It plays an important role in basic biological processes. It affects many things, like inflammation, detox, stress management, and circadian rhythms. It does this by helping to regulate balance in cells.
The scary thing is, as we age, our NAD+ levels drop significantly—down as much as 50% by midlife and further as we age. People feel visible signs of aging, including fatigue, reduced meta bolism, and cognitive decline. A decline in sirtuins, a protein associated with aging and longevity, accompanies this.
Research shows that higher NAD+ levels can improve mitochondrial function. They can also lower oxidative stress and activate sirtuins. Sirtuins are proteins linked to aging and longevity. Together, these effects promote overall health, increased resistance to age-related diseases, and a more youthful appearance.
Elevating NMN levels is an excellent method to alter your aging process!
What are the benefits of NMN?
NMN is a direct precursor to NAD+ and is a powerful solution for replenishing this important molecule. By taking NMN supplement, your body can make NAD+ more easily. This helps restore energy in cells and supports repair processes that are important for a long life.
Various studies in humans and animals have shown that NMN is exceptionally beneficial to health. One important way that NMN increases NAD+ is by boosting cellular meta bolism. It does this by increasing mitochondrial activity, which slows down cellular aging.
As we age, our cellular meta bolism increasingly dysregulates and becomes less efficient. However, NMN can assist in realigning your meta bolism back to normal.
If you want to know more about NMN, please read this article: Is NMN the Secret to Anti-Aging? Everything You Need to Know About NMN Supplements.
Human clinical trials and preclinical studies provide a lot of evidence to support the benefits of NMN supplementation:
1. Increase NAD+ levels
Okabe and others published a study in Frontiers in Nutrition. They found that taking 250 mg of NMN daily for four weeks increased blood NAD+ levels by 40%. Researchers observed no negative effects.
2. Enhance oxygen utilization
Liao et al. published a study in the Journal of the International Society of Sports Nutrition. It found that taking NMN improved oxygen absorption and use. This is important for exercise endurance. The study emphasized a dose-dependent benefit, with the higher the dose (600-1200 mg/day), the better the effect.
3. Metabolic benefits
A study by Yoshino et al. in Science found that taking NMN helped older women with prediabetes. It improved their muscle insulin sensitivity and promoted better metabolic health.
4. Improved physical function
Kim and others reported in Nutrition that taking NMN for 12 weeks improved leg function in older Japanese individuals. It also reduced sleepiness, especially when taken in the afternoon.
5. Improved walking speed
A study published in npj Aging by Igarashi and others found that older men who took NMN for 12 weeks walked faster. This faster walking shows that their physical activity improved.
6. Animal studies
Preclinical studies have shown that NMN helps improve blood flow and increase exercise endurance. It also enhances mitochondrial function, protects kidney health, and restores gene expression related to circadian rhythm in older mice. These studies suggest that NMN has great potential to address various aspects of aging and metabolic health.
Mark Hyman, MD, is a well-known expert in functional medicine. He is also a 15-time bestselling author. In this podcast, he talks with Andrew Salzman, MD, who is the Chief Medical Officer of Wonderfeel.
They discuss the health benefits of NMN and how to improve NAD levels. Dr. Hyman also takes NMN supplements daily.
While these findings are promising, researchers need to conduct more human studies. We need to confirm the long-term safety and effectiveness of NMN supplementation in different populations. Nevertheless, it remains the optimal method to postpone aging.
How to Choose an NMN Supplement?
Selecting an NMN supplement can often be challenging. More NMN supplements are coming to the market. Scientific studies show that NMN supplements may play a key role in future anti-aging technology.
When choosing the best NMN supplement for you, consider these factors: delivery method, dosage, quality, purity, and ingredients.
1.NMN Delivery Method
NMN supplements come in many forms. The most common are capsules and powders. They are also available as chewable tablets, sublingual powders, intranasal sprays, transdermal creams, serums, and liposomal formulations. While this variety provides flexibility, you should focus on methods that clinical evidence supports.
One factor to consider is that clinical trials have mostly tested NMN taken as a powder or capsule. No studies have shown that alternative forms like sublingual powders, intranasal sprays, or skin creams are safe or effective.
A study by Grozio et al. in Nature meta bolism found NMN-specific transporters in the small intestine. This suggests that taking NMN by mouth is a natural way for the body to absorb it. This process allows for quick conversion to NAD+ for cellular function.
2. NMN Dosage
The dosages of NMN supplements can vary a lot. Following evidence-based guidelines for safety and effectiveness is important. For example, AIDEVI NMN has 300 mg of NMN in each serving. This amount matches the dose used in clinical trials.
Okabe and others found that NAD+ levels went back to normal after stopping supplementation. This demonstrates that ongoing intake is necessary to maintain long-term benefits. and highlights the importance of choosing a product with a proven dosage and maintaining regular supplementation for optimal results.
3. NMN Quality
Unlike drugs, which require FDA approval to enter the market, supplements are subject to different regulatory standards. Supplements must meet production standards and rules against false claims. However, enforcement happens only after the product is on the market.
Therefore, it is critical to choose a trustworthy NMN supplement manufacturer. Reputable brands openly share their product label claims, conduct rigorous quality testing, and obtain independent third-party certification to ensure transparency and reliability.
AIDEVI's NMN products stand out with their rigorous quality assurance. They are FDA-reviewed and certified by multiple trusted organizations, including COA, GMP, SGS, and COO.
AIDEVI manufactures its products in GMP-compliant facilities. Different agencies regularly check them to ensure high quality and safety standards. When choosing AIDEVI's NMN supplements, you can be confident in its purity, safety, and efficacy.
4. Purity
The best NMN supplements use exceptionally pure NMN. This helps them work well and reduces the chance of side effects.
Research shows that well-formulated NMN supplements can help restore cell and tissue vitality without causing harmful side effects.
Choosing supplements from trusted manufacturers is important. They should focus on purity and offer third-party testing. They must also have strict quality control measures. This guarantees that the NMN you consume is of the highest quality to promote optimal health and well-being.
What is the best way to deliver NMN: capsules, liposomes, or sublinguals?
Choosing the right method of NMN delivery is critical to the effectiveness of NMN. Capsules are the preferred method of delivery for treatment in scientific studies.
They are effective in raising NAD+ levels. Capsules are currently the most reliable way to deliver NMN. They help ensure that the body absorbs and utilizes it well.
Alternative methods like liposomes and sublingual NMN supplements are getting a lot of attention today. However, there is not enough scientific evidence to prove that they have better bioavailability than capsules.
Dr. Michael Levitt, Chief Scientific Advisor at AIDEVI, said these delivery methods are complex. He added that researchers need to conduct more studies to compare their effectiveness to traditional capsules. Until more data is available, capsules are the best choice for NMN supplements. Many scientific studies support this view.
NMN Supplementation Questions
Is it OK to take NMN daily?
Absolutely! As we age, our NAD+ levels naturally decline, which can affect our overall health. Regular daily supplementation with NMN can help replenish these declining NAD levels, boosting our energy and vitality.
Remember, the journey to health restoration with NMN is a long journey, not a sprint. Daily consistency is essential to optimal results.
Can you get NMN from food alone?
You can get NMN in your daily life through foods like edamame, broccoli, cucumber, cabbage, avocado, and certain fruits. Our cells produce NMN in two main ways, in addition to getting it from food. They can create it from nicotinamide (NAM), a water-soluble form of vitamin B3, or from nicotinamide riboside (NR). You can find both NAM and NR in various foods.
Scientists believe that although diet can help produce NAD+. This molecule is important for cellular energy and repair. However, NMN in food is not enough to make up for the NAD+ we lose as we age. Therefore, we still need additional NMN supplementation to promote NAD+ synthesis.
How to maximize the absorption and utilization of NMN supplements
After reading this, you may be wondering, "How can I naturally increase my NAD+ levels?" While NMN supplementation is an effective way to increase NAD+ levels, specific lifestyle combinations can further enhance NAD+ synthesis.
1. Regular exercise
Proper exercise places energy demands on your cells, prompting your body to increase NAD+ production. Exercise methods such as aerobic exercise and strength training are particularly effective.
2. Intermittent fasting diet
Research shows that intermittent fasting or calorie restriction can boost NAD+ production. This happens by activating metabolic pathways like sirtuins. Before starting an intermittent fasting diet, be sure to increase the fasting time step by step.
3. Eat fermented foods
Fermented products such as yogurt, kimchi, and kombucha contain enzymes that enhance NAD+ availability, helping to increase levels.
4. Achieving Ketosis
Entering ketosis with a low-carb, high-fat diet makes the body use fat for energy. This process helps increase NAD+ production. This metabolic shift can support the healthy aging process.
5. Moderate Fructose Consumption
The fructose in fruits like apples, pears, grapes, and honey helps activate enzymes. These enzymes promote the production of NAD+, which is key to maintaining overall health.
Incorporating these practices into your lifestyle can lead to sustained improvements in NAD+ levels over time. To get the best results, think about using these practices with NMN supplements. NMN enhances the production of NAD+ within the body. This can help you enjoy both short-term and long-term benefits.
Can I buy NMN supplements online?
You can conveniently locate NMN supplements online. Many trusted retailers and health supplement websites (like AIDEVI) sell them.
Who should avoid taking NMN supplements?
Pregnant or breastfeeding individuals and those with underlying medical conditions should consult a healthcare professional before using NMN supplements. Ensure safety and suitability first.
What are the side effects of NMN overdose?
Normal use will not cause problems, but taking too much at once can lead to an NMN overdose.
This may result in different side effects. Mild side effects may include digestive discomfort, nausea, and headaches. In contrast, significant side effects may involve severe digestive problems, liver problems, and potential interactions with other medications. Sticking to the suggested dosage is crucial to prevent these negative effects and guarantee safe supplementation.
What are the best NMN and resveratrol combination supplements?
AIDEVI's Chief Scientific Advisor, Professor Michael Levitt, is a well-known scientist. He is a tenured professor at Stanford University. He is also a member of the National Academy of Sciences and won the Nobel Prize in 2013. Professor Michael played a key role in creating AIDEVI's premium NMN formula.
This new blend mixes NMN with resveratrol, fruit and vegetable powders, PQQ, and anthocyanins. It aims to improve cellular health and activate sirtuins.
You dose resveratrol at 100 mg per serving. This helps support healthy cell function. It works together with NMN to activate sirtuin genes. This process also increases NAD+ levels.
All while avoiding the risks associated with excessive resveratrol dosages, such as impaired cellular processes and delayed healing.
The formula also addresses oxidative stress, a key factor in the efficacy of NMN and NAD+. By incorporating antioxidants and bioactive compounds, AIDEVI NMN enhances the delivery and function of NMN at the cellular level.
AIDEVI suggests taking two capsules each day. This gives you 600 mg of NMN, with 300 mg in each capsule. You also get 100 mg of resveratrol, 50 mg of fruit and vegetable powders, 20 mg of anthocyanins, and 10 mg of PQQ. This dosage is both safe and highly effective to promote cellular health and longevity.
Potential Side Effects: Are NMN Supplements Safe?
Clinical trials of NMN supplementation and higher NAD+ levels have not shown any major side effects. No studies have found serious problems with increasing NAD+ levels in the body. However, as with other supplements, we should continue to be concerned about long-term effects. Researchers need to conduct ongoing studies to fully understand the benefits and ensure long-term safety.
Approaching new supplements with caution is critical. Before you start or change any diet that includes NMN or NAD+ supplements, talk to your doctor. This will help make sure it suits your health needs and condition.
Age Better by Choosing the NMN Supplement That Best Fits Your Needs
The science behind NMN supplementation continues to evolve, promising new breakthroughs on its potential health benefits. As researchers progress in their studies, they will gain a more complete understanding of how NMN can restore NAD+ levels to slow aging. Current clinical trials are investigating the pharmacodynamics of high-dose NMN, its effects on cardiometabolic health, muscle recovery, physical activity, and more.
The field of longevity science is still new. However, new evidence shows that NAD+ and NMN play a key role in healthy aging. By using a good NMN supplement like AIDEVI and adopting healthy habits, people can support their body's rejuvenation.
This may help them "turn back" their biological clock to a younger state. Exciting advances in this field promise to change the way we approach aging and overall health.