Accroding the AIDEVI Lab USA reseachments , the NMN is only stable to supply the NAD+ to cell , but its transfer NAD+ is less after a long Journey to the blood of human .NMN Supplements have similar problem from the liver to blood . 

NMN (Nicotinamide Mononucleotide) is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a crucial coenzyme present in all cells, vital for cellular health and energy metabolism. As we age, the levels of NAD+ diminish, which is why many researchers are interested in elevating NAD+ levels to potentially delay aging and boost health.

1.How is NMN introduced into the digestive system?

Orally: This is the most common method, typically in the form of NMN capsules or powders.

Sublingual absorption: E.g., using sublingual drops. This method is believed to introduce NMN more rapidly into the bloodstream and bypass some of the digestion processes.

2.Efficiency:

Once NMN is ingested and enters the digestive system, it's converted to NAD+ in the intestines. However, there are studies suggesting that, before entering the cell, NMN might first be converted to another NAD+ precursor, Nicotinamide Riboside (NR), which then gets converted to NAD+. This implies that not all NMN directly gets converted to NAD+.

Nevertheless, supplementing with NMN can effectively elevate NAD+ levels in the body, although the efficiency might vary based on factors such as dosage, bioavailability, and individual differences.

3.How to improve the efficiency of NMN?

Enhance bioavailability: Opt for NMN forms or products that have a better bioavailability, like a combination of oral and sublingual intake.

Co-ingestion with other substances: Some research suggests that taking NMN with other compounds, like fatty acids or specific carriers, might enhance absorption.We already tested the AIDEVI NMN18000 , AIDEVI NMN21000 , the results show compounds formula of NMN anti aging supplements is effectiveness in the transfer to NAD+ level of the blood . 

Correct dosing: Stick to recommended dosages and adjust as necessary based on results. AIDEVI Canada Lab shown 100mg–200mg NAD+ is good one day for human body absorbtion. That meant, we need to provide 600mg-1000mg NMN to body . 

Other lifestyle habits: Healthy diet and exercise can also help increase NAD+ levels and its utilization.

How about the injection NAD+ into the body ?

Injecting NAD+ directly into the body has garnered attention, especially among biohackers and those looking for rapid health and wellness benefits. The primary methods of introducing NAD+ directly into the bloodstream include intravenous (IV) infusions and intramuscular injections.

Benefits and Considerations:

1.Rapid Elevation of NAD+ Levels: Unlike oral or sublingual supplements which need to be digested and metabolized, direct injections can rapidly elevate cellular NAD+ levels, offering potentially quicker benefits.

2.Bypassing Digestive Metabolism: Direct injection means that the NAD+ doesn't undergo any gastrointestinal metabolism, ensuring almost full availability.

3.Applications: IV infusions of NAD+ have been explored for various uses, including:

Addiction and withdrawal recovery

Boosting energy levels

Cellular rejuvenation and anti-aging

Mental clarity and cognitive function enhancement

4.Safety and Side Effects: While generally considered safe, IV NAD+ therapy can have some side effects. These may include:

Flu-like symptoms

Nausea

Chest tightness

Lightheadedness
The infusion rate and the individual's response can influence these side effects. Slow administration usually mitigates some of these effects.

5.Cost: IV NAD+ treatments can be expensive, often more so than taking oral or sublingual supplements.

6.Regulation and Purity: Given that it's a more direct method of administration, ensuring the purity of the NAD+ solution is paramount. Additionally, regulation around these therapies may differ from country to country. It's crucial to approach reputable clinics or providers.

7.Research: While there are anecdotal accounts of the benefits of IV NAD+, more rigorous clinical research is needed to determine its efficacy, optimal dosing, and long-term effects.

AIDEVI wish improve the efficiency of NAD+ level transfermation of NMN and NMN Supplement to achieve the Anti Aging goals , make the health physical body .

In the near future , AIDEVI NAD+ Capsule will be out for global customers .